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KMID : 0812020060120010025
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Korean Journal of Neurogastroenterology and Motility
2006 Volume.12 No. 1 p.25 ~ p.30
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Usefulness of Multichannel Intraluminal Impedance-pH metry in Patients with Suspected GERD Presenting with Typical or Atypical Symptoms
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Han Dae-Hee
Lee Joon-Seong
Ryu Chang-Beom
Kim Yong-Dae
Im Hee-Hyuk
Jung In-Seop
Ko Bong-Min
Hong Su-Jin
Kim Jin-Oh
Cho Joo-Young
Lee Moon-Sung
Shim Chan-Sup
Kim Boo-Sung
Jung Yun
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Abstract
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Background/Aims: To investigate the usefulness of multichannel intraluminal impedance-pH metry (MII-pH) as a diagnostic tool for gastroesophageal reflux disease (GERD): 1) the usefulness of MII-pH to increase the diagnostic sensitivity of GERD; and 2) to analyze whether various GERD symptoms were correlated with acid and nonacid reflux in patients with a positive symptom index (SI).
Methods: We retrospectively compared the results of pH-metry and the results of MII-pH metry from the data of MII-pH in 74 patients with suspected GERD.
Results: 1) Twenty out of 74 patients were diagnosed with GERD by pH monitoring, and an additional 15 cases had a positive SI (> 50%). Out of the remaining 39 patients, a positive SI for nonacid reflux was present in nine patients. A total of 17 cases were added to the GERD diagnosis including eight patients who showed an increase in total bolus reflux time percentage by MII-pH. 2) Regurgitation was more commonly observed with acid reflux in 29 patients with positive SI, but heartburn and noncardiogenic chest pain were more commonly correlated to nonacid reflux.
Conclusions: Multichannel intraluminal impedance-pH metry is a sensitive method for the diagnosis of GERD and informs the correlation between symptoms and reflux. (Kor J Neurogastroenterol Motil 2006;12:25-30)
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KEYWORD
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GERD, Multichannel intraluminal impedance-pH metry
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